Education

Research & Education

  • Trial site for SLATE – Stereotactic Laser Ablation for Temporal Lobe Epilepsy
  • Combining intracranial electrophysiological recording and imaging to develop biomarkers for hippocampal epilepsy
  • Development and testing of a cortical visual prosthesis (a multi-institutional collaboration led by V. Leo Towle PhD)
  • Understanding the deep brain circuits involved in attention and memory (collaboration with the Departments of Neurobiology and Psychology)
  • Investigating genetic susceptibilities in primary generalized epilepsy (collaboration with the Department of Neurobiology)
  • Using neurophysiological recordings and mathematical analysis to better understand how central motor systems coordinate limb movement
  • Understanding the role of seizures in the pathophysiology of neurocysticercosis
  • Understanding and preventing SUDEP
  • BOOST III Trial: phase III RCT to evaluate outcome with PbtO2 directed therapy vs. ICP directed therapy in severe TBI
  • MISTIE III: Minimally Invasive Surgery Plus rt-PA for intracerebral Hemorrhage Evacuation is a phase III RCT evaluating outcome in patients with ICH treated with catheter directed lytic therapy
  • CLEAR III: Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III
  • Penetrating traumatic brain injury
  • Prognosis after cardiac arrest
  • Stroke code activation demographics
  • Neurologic complications of ventricular assist devices
  • A Double-Blind, Randomized, Multicenter, Placebo Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Fingolimod 0.5 mg Administered Orally Once Daily Versus Placebo in Patients with Chronic Inflammatory
  • Demyelinating Polyradiculoneuropathy
  • Assessment of intermuscular coherence as a biomarker for ALS and commercialization of a diagnostic test for ALS
  • SOD1 designed ankyrin repeat protiens (DARPins), a genetically engineered antibody mimetic protein, as a treatment for ALS
  • Unconventional translation of the expanded repeat of a gene, C9ORF72
  • Targeting the integrated stress response in ALS
  • Studies of Theiler’s virus-induced immune mediated demyelinating disease, a model of MS
  • ACTIsSIMA: Double-Blind, controlled phase IIB study of Modified Stem Cells (SB623) in the treatment of motor deficits in ischemic stroke
  • CREST-II: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
  • RESPECT-ESUS: A randomized, double-blind evaluation in secondary stroke prevention comparing the efficacy and safety of the thrombin inhibitor dabigatran etexilate vs acetylsalicylic acid in patients with embolic stroke of underdetermined source (ESUS)