Research

Sasha Wu, MD

  1. Board certification
  • Neurology, American Board of Psychiatry and Neurology (remove the psychiatry, American Board of Psychiatry and Neurology)
  • Epilepsy, American Board of Psychiatry and Neurology
  • Epilepsy monitoring, American Board Of Clinical Neurophsiology
  1. Clinical Interest
  • Medical and surgical treatment of drug resistant epilepsy.
  • Minimally invasive epilepsy surgery
  • Inflammation, antibody related epilepsy
  • Clinical neurophysiology, EEG
  1. Research Interest
  • Dr. Wu's research focuses on the investigation of EEG biomarkers for the epileptogenic tissue, such as infra slowing activity and High Frequency Oscillations using intracranial EEG recordings.  The goal of the research is to help in delineating the epileptic brain tissue for epilepsy surgery and to improve the surgical outcome. 
  1. Selected Publications:
  • Lee S, Issa NP, Rose S, Tao JX, Warnke PC, Towle VL, van Drongelen W, Wu S. DC shifts, high frequency oscillations, ripples and fast ripples in relation to the seizure onset zone. Seizure. 2019 May 03. PMID: 31101405.
  • Plass J, Ahn E, Towle VL, Stacey WC, Wasade VS, Tao J, Wu S, Issa NP, Brang D. Joint Encoding of Auditory Timing and Location in Visual Cortex. J Cogn Neurosci. 2019 Jul; 31(7):1002-1017. PMID: 30912728.
  • Liu X, Issa NP, Rose S, Wu S, Sun T, Towle LV, Warnke PC, Tao JX. The first-hour-of-the-day sleep EEG reliably identifies interictal epileptiform discharges during long-term video-EEG monitoring. Seizure. 2018 Dec; 63:48-51. PMID: 30399461.
  • Issa NP, Lee S, Wu S, Rose S, Towle VL, Warnke PC, van Drongelen W, Tao JX. Reply to "which small sharp spikes are benign epileptiform transients of sleep?" Clin Neurophysiol. 2018 Nov; 129(11):2495-2496. PMID: 30268708.
  • Bruzzone MJ, Issa N, Rose S, Warnke P, Towle VL, Tao JX, Wu S. Insights Into the Therapeutic Effect of Responsive Neurostimulation Assessed With Scalp EEG Recording: A Case Report. J Clin Neurophysiol. 2018 Sep; 35(5):438-441. PMID: 29023305.
  • Tao JX, Issa NP, Wu S, Rose S, Collins J, Warnke PC. Interstitial Stereotactic Laser Anterior Corpus Callosotomy: A Report of 2 Cases with Operative Technique and Effectiveness. Neurosurgery. 2018 Jul 05. PMID: 29982584.
  • Issa NP, Wu S, Rose S, Towle VL, Warnke PC, Tao JX. Small sharp spikes as EEG markers of mesiotemporal lobe epilepsy. Clin Neurophysiol. 2018 Sep; 129(9):1796-1803. PMID: 30005212.
  • Daif A, Lukas RV, Issa NP, Javed A, VanHaerents S, Reder AT, Tao JX, Warnke P, Rose S, Towle VL, Wu S. Antiglutamic acid decarboxylase 65 (GAD65) antibody-associated epilepsy. Epilepsy Behav. 2018 03; 80:331-336. PMID: 29433947.
  • Tao JX, Wu S, Lacy M, Rose S, Issa NP, Yang CW, Dorociak KE, Bruzzone M, Kim J, Daif A, Choi J, Towle VL, Warnke PC. Stereotactic EEG-guided laser interstitial thermal therapy for mesial temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 2018 May; 89(5):542-548. PMID: 29183959.
  • Ali A, Wu S, Issa NP, Rose S, Towle VL, Warnke P, Tao JX. Association of sleep with sudden unexpected death in epilepsy. Epilepsy Behav. 2017 11; 76:1-6. PMID: 28917499.
  • Jiang H, Schuele S, Rosenow J, Zelano C, Parvizi J, Tao JX, Wu S, Gottfried JA. Theta Oscillations Rapidly Convey Odor-Specific Content in Human Piriform Cortex. Neuron. 2017 Apr 05; 94(1):207-219.e4. PMID: 28384472.
  • Tao JX, Issa N, Collins JW, Wu S, Rose S, Warnke P. Homonymous hemianopsia after MR-guided stereotactic laser amygdalohippocampectomy. Epilepsy Behav. 2017 01; 66:140-141. PMID: 27993511.
  • Serafini A, Issa NP, Rose S, Wu S, Warnke P, Tao JX. TIRDA Originating From Lateral Temporal Cortex in a Patient With mTLE Is Not Related to Hippocampal Activity. J Clin Neurophysiol. 2016 Dec; 33(6):e34-e38. PMID: 27753735.
  • Wang S, Graf S, Xu J, Issa NP, Ali A, Rose S, Wu S, Jacobsen J, Warnke P, Tao JX. The incidence of peri-ictal prone position in patients with generalized convulsive seizures. Epilepsy Behav. 2016 08; 61:158-161. PMID: 27351726.
  • Serafini A, Lukas RV, VanHaerents S, Warnke P, Tao JX, Rose S, Wu S. Paraneoplastic epilepsy. Epilepsy Behav. 2016 08; 61:51-58. PMID: 27304613.
  • Wu S, Issa NP, Rose SL, Ali A, Tao JX. Impact of periictal nurse interventions on postictal generalized EEG suppression in generalized convulsive seizures. Epilepsy Behav. 2016 05; 58:22-5. PMID: 26994879.
  • Wu S, Tao XJ, Issa N, Rose S, Warnke P. MR-guided laser interstitial thermal therapy for the treatment of medically refractory epilepsy. Int J Neurol Neurother. 2016; (3):42.
  • Tao J, Liebenthal J, Wu S, Rose S, Ebersole JS. Author response:. Neurology. 2015 Sep 29; 85(13):1185-6. PMID: 26688873.
  • Rose S, Wu S, Jiang A, Kim J, Tao JX. Neurogenic pulmonary edema: An etiological factor for SUDEP? Epilepsy Behav. 2015 Nov; 52(Pt A):76-7. PMID: 26409134.
  • Brang D, Towle VL, Suzuki S, Hillyard SA, Di Tusa S, Dai Z, Tao J, Wu S, Grabowecky M. Peripheral sounds rapidly activate visual cortex: evidence from electrocorticography. J Neurophysiol. 2015 Nov; 114(5):3023-8. PMID: 26334017.
  • Tao JX, Sandra R, Wu S, Ebersole JS. Should the "Back to Sleep" campaign be advocated for SUDEP prevention? Epilepsy Behav. 2015 Apr; 45:79-80. PMID: 25875185.
  • Liebenthal JA, Wu S, Rose S, Ebersole JS, Tao JX. Association of prone position with sudden unexpected death in epilepsy. Neurology. 2015 Feb 17; 84(7):703-9. PMID: 25609764.
  • Wu S, Kunhi Veedu HP, Lhatoo SD, Koubeissi MZ, Miller JP, Lüders HO. Role of ictal baseline shifts and ictal high-frequency oscillations in stereo-electroencephalography analysis of mesial temporal lobe seizures. Epilepsia. 2014 May; 55(5):690-8. PMID: 24725106.
  • Lee A, Wu S, Zhou X, Liebenthal J, Rose S, Tao JX. Periictal autonomic dysfunction and generalized postictal EEG suppression in convulsive seizures arising from sleep and wakefulness. Epilepsy Behav. 2013 Sep; 28(3):439-43. PMID: 23891764.