Shasha Wu, MD PhD

Assistant Professor
Director, Epilepsy Monitoring Service

Patient Calls: 773-702-6222
Fax: 773-834-4800

Shasha Wu, MD, PhD, specializes in the diagnosis and management of adult epilepsy. Using sophisticated EEG and computer imaging techniques, she works to identify the source of a patient's seizures and determine the best possible course of treatment.

Education & Training
  • Fellowship: University Hospital, (Case Western Reserve University)
  • Fellowship: University of Pittsburgh (neurology research)
  • Residency: Fletcher Allen Health Care, (University of Vermont)
  • Internship: AtlantiCare Regional Medical Center
  • M.D.: Baotou Medical College, China
  • PhD: Peking University School of Medicine, Beijing, China
Board Certification
  • Neurology, American Board of Psychiatry and Neurology
  • Psychiatry, American Board of Psychiatry and Neurology
Clinical Interests
  • Epilepsy
  • Clinical neurophysiology
  • EEG
Research Interests
  • Dr. Wu's current research focuses on the application of Direct Current shift and High Frequency Oscillations in invasive pre-surgical EEG recordings. In the past, she has worked on the ways in which brain trauma -- including stroke and seizure -- affects neurons. Her goal is to improve quality of life for patients experiencing chronic seizures.
Society Memberships
  •  American Academy of Neurology
  • American Clinical Neurophysiology Society
  • American Epilepsy Society
Selected Publications
  • Wu S, Lüders H et al.  Direct Current Shifts and High Frequency Oscillations (HFO) in Mesial Temporal Lobe Seizures.  (In process).
  • Li W, Wu S, Ahmad M, Jiang JF, Liu H, Nagayama T, Rose M, Tyurin VA, Chen J, Kagan VE, Graham SH. (2009) The Cyclooxygenase Activity, But Not the Peroxidase Activity of Cyclooxygenase 2 is Required for Neurotoxicity in Hypoxic Ischemic Injury. J Neurochem. 2010 May 113(4):965-77.
  • Li W, Wu S, Hickey RW, Rose ME, Chen J, Graham SH. (2008) Neuronal Cyclooxygenase-2 Activity and Prostaglandins PGE2, PGD2, and PGF2alpha Exacerbate Hypoxic Neuronal Injury in Neuron-enriched Primary Culture.  Neurochem Res. 2008, Mar; 33(3)490-9.
  • Tehranian R, Rose ME, Vagni V, Griffith RP, Wu S, Maits S, Zhang X, Clark RS, Dixon CE, Kochanek PM, Bernard O, Graham SH. (2006) Transgenic mice that over express the anti-apoptotic Bcl-2 protein have improved histological outcome but unchanged behavioral outcome after traumatic brain injury. Brain Res.  2006, Jul 26; 1101(1) 126-35.
  • Wu S.  Zhou L., Xiao X., Rose M., Graham S., (2004). c-FLIP-L Recombinant Adeno-Associated Virus Vector Infection Inhibit Fas-mediated but not NGF withdrawal-mediated Cell Death in PC12 cells. Brain Res Mol Brain Res. 2004 Mar 17; 122(1):79-87.