Rong Zhai

University of Alabama at Birmingham
Birmingham, AL
PhD - Neurobiology

Baylor College of Medicine
Houston, TX
postdoctoral Fellow - Neurogenetics

Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's disease.
Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's disease. Life Sci Alliance. 2024 Nov; 7(11).
PMID: 39237365

Loss of Fic causes progressive neurodegeneration in a Drosophila model of hereditary spastic paraplegia.
Loss of Fic causes progressive neurodegeneration in a Drosophila model of hereditary spastic paraplegia. Biochim Biophys Acta Mol Basis Dis. 2024 10; 1870(7):167348.
PMID: 38986817

Model matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe).
Model matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe). Lab Anim (NY). 2024 Jul; 53(7):161-165.
PMID: 38914824

High-resolution, high-throughput analysis of Drosophila geotactic behavior.
High-resolution, high-throughput analysis of Drosophila geotactic behavior. bioRxiv. 2024 Jun 08.
PMID: 38895419

Reduction of spermine synthase enhances autophagy to suppress Tau accumulation.
Reduction of spermine synthase enhances autophagy to suppress Tau accumulation. Cell Death Dis. 2024 May 13; 15(5):333.
PMID: 38740758

Copper enhances aggregational toxicity of mutant huntingtin in a Drosophila model of Huntington's Disease.
Copper enhances aggregational toxicity of mutant huntingtin in a Drosophila model of Huntington's Disease. Biochim Biophys Acta Mol Basis Dis. 2024 01; 1870(1):166928.
PMID: 38660915

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome.
Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome. EMBO Mol Med. 2023 11 08; 15(11):e17833.
PMID: 37702369

MicroRNA-Mediated Obstruction of Stem-loop Alternative Splicing (MIMOSAS): a global mechanism for the regulation of alternative splicing.
MicroRNA-Mediated Obstruction of Stem-loop Alternative Splicing (MIMOSAS): a global mechanism for the regulation of alternative splicing. bioRxiv. 2023 Jun 28.
PMID: 37425843

Sorbitol reduction via govorestat ameliorates synaptic dysfunction and neurodegeneration in sorbitol dehydrogenase deficiency.
Sorbitol reduction via govorestat ameliorates synaptic dysfunction and neurodegeneration in sorbitol dehydrogenase deficiency. JCI Insight. 2023 05 22; 8(10).
PMID: 37014713

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome: mechanism of action and therapeutic potential.
Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome: mechanism of action and therapeutic potential. bioRxiv. 2023 Apr 10.
PMID: 37034775