Clinical Trials
The Department of Neurology is actively involved in clinical trials to determine the effectiveness of new medications to treat neuromuscular diseases and disorders. If you are interested in receiving additional information or participating in a trial, please e-mail or call the persons listed below. Please note that enrollment is currently closed for some of the trials.


Stroke - Completed Trials


CRESCENDO
  Enrollment is CLOSED; data being analyzed
 
Randomized trial of a new investigational agent, rimonabant, for prevention of stroke and heart attacks in overweight patients with vascular risk factors.

  Principle Investigator: James Brorson MD
  Study Coordinator: Christi Kordeck, 773-834-4604


HeADDFIRST
Hemicraniectomy and Durotomy upon Deterioration for Massive Hemispheric Infarction Related Swelling Trial
  Enrollment is CLOSED; data being analyzed
 
This purpose of this study is to evaluate the benefits of surgical decompression to decrease the morbidity and mortality from large hemispheric stroke associated brain swelling. The University of Chicago Hospital will facilitate safe, rapid transport and provide feedback to the referring physician/facility.
 
Eligibility Criteria:
  • 18-75 years of age
  • Acute MCA stoke
  • Must develop brain swelling of a specific magnitude
  Principle Investigator: Jeffrey Frank MD
  Study Coordinator: Christi Kordeck