Clinical Trials
The Department of Neurology is actively involved in clinical trials to determine the effectiveness of new medications to treat neuromuscular diseases and disorders. If you are interested in receiving additional information or participating in a trial, please e-mail or call the persons listed below. Please note that enrollment is currently closed for some of the trials.


Multiple Sclerosis (MS) - Completed Trials; data being analyzed


Anti-B Cell Antibody (Rituxan) for Progressive MS
  Enrollment is CLOSED; data is being analyzed
 
The purpose of this two and a half year study is to investigate an Anti-B cell antibody in the treatment of Primary Progressive MS.

  Principle Investigator: Anthony Reder MD
  Sub-Investigator(s): Barry Arnason MD, Adil Javed MD, Avertano Noronha MD
  Study Coordinator: Mildred Valentine

BEYOND Study for Relapsing/Remitting MS
  Enrollment is CLOSED; data is being analyzed
 
The purpose of this two year study is to determine:
  1. If an experimental dose of a currently approved drug is safe, tolerable, and more effective than the currently approved dose.
  2. Which of two commonly used drugs is safer, more tolerable, and more effective in treating this disease.
  Principle Investigator: Barry Arnason MD
  Sub-Investigator(s): Roumen Balabanov MD, Adil Javed MD, Agnes Kim MD, Avertano Noronha MD, Anthony Reder MD, Darshan Shah MD
  Study Coordinator: Mildred Valentine

Novantrone in MS
  Enrollment is CLOSED; data is being analyzed
 
This is a phase IV monitoring study of the effects of Mitoxantrone/Novantrone in active MS. This drug was recently approved by the FDA, and is a form of chemotherapy that reduces the white blood cells that attack the brain. WBC, liver function, and cardiac function will be monitored.

  Principle Investigator: Anthony Reder MD
  Study Coordinator: Mildred Valentine

Rebif vs. Copaxone in Relapsing/Remitting MS
  Enrollment is CLOSED; data are being analyzed
 
The purpose of this study is to compare the safety and effectiveness of two FDA approved drugs for the treatment of relapsing/remitting MS.

  Principle Investigator: Anthony Reder MD
  Sub-Investigator(s): Barry Arnason MD, Avertano Noronha MD
  Study Coordinator: Mildred Valentine